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The Evolving Regulatory Landscape of 3D-Printed Medical Products

The concept of making personalized devices doesn’t require new regulatory processes During the past year, my email inbox has been consistently pinged by law firms advertising seminars and workshops...

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The Patient’s Voice Enhances FDA’s Approach to Drug Review and Development

Public meetings helped fulfill an FDA commitment one year ahead of schedule read more

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Utility NERC Compliance Programs Challenged by New Risk-Based Approach

Solid record-keeping and document management are key If compliance with the North American Electric Reliability Corp. (NERC) Reliability Standards wasn’t complex enough, registered utilities must also...

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Inside Quality Digest Live: Jan. 13, 2017

FDA’s MRI program, better coaching, Olympus Vanta XRF analyzer, and more I’m pinch-hitting for my co-host Mike Richman in the wrap-up of this past Friday’s episode of Quality Digest Live. Mike was off...

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New CDER Guidance Could Affect Quality Management Efforts

Be proactive in anticipation of new leadership and direction at the FDA read more

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FDA Touts Improved IDE Review Stats

Nearly 75 percent of Investigational Device Exemption studies are fully approved within two cycles read more

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FDA Answers (Some) Medical Device Cybersecurity Concerns

For premarket approval, it’s mostly common sense—with a few caveats Anew FDA guidance calls on the medical device community to be more proactive when it comes to developing a solid set of...

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FDA Eases Up a Bit on Enforcement Gas Pedal

Fewer warning letters, but CAPAs continue to garner the most citations Medical device warning letters and domestic inspections continue to show a slow decline, according to a new report issued by the...

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Management Responsibility for GMP Oversight and Control

Do you know where your daily operation stands at any given moment? Historically, the Food and Drug Administration (FDA) has cited the Supreme Court decisions of United States v. Dotterweich (1943) and...

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Will You Be Ready for a FSMA Audit?

Four tips to pass an FDA audit Although the FDA’s Food Safety Modernization Act (FSMA) was passed in 2011, the reality is that the rules that went along with the law—and that truly define how it will...

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How to Prepare for an FDA Inspection

Five tips to help you get ready During the past several years, the FDA has been more aggressive and active in performing medical device company inspections. This has led to a far greater number of...

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FDA Proposes Cybersecurity Guidelines for Medical Devices

Stakeholders have 90 days to submit comments to the FDA Iwrote last month about the need to increase security for imaging devices in hospitals. The devices I cited store both personal and medical...

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Border Crossings

Working with partners to verify the safety of imported produce One of the vivid images that sticks with me from my tenure at the Food and Drug Administration (FDA) is of the port of entry at Nogales,...

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Addressing Human Factors Relating to Combination Products

FDA seeks comments on new draft guidance Combination products represent an important and growing category of therapeutic and diagnostic products under the U.S. Food and Drug Administration’s (FDA)...

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Why FMEA Is Not ISO 14971

Medical device risks aren’t solely a function of failure If you’re still using failure mode and effects analysis (FMEA) as your methodology to capture medical-device risk management activities, then...

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The Rise and Fall of Theranos

So many lessons in a drop of blood read more

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Modernizing the Pharmaceutical Manufacturing Base

Continuous manufacturing has a strong impact on drug quality If we used a time machine to transport a pharmaceutical scientist from the 1960s into a current pharmaceutical production plant, it might...

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Six Tips to Make Sure Your 510(k) Submission Is Accepted

Planning and organization will help you avoid the FDA’s refusal read more

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FDA Introduces the Pre-RFD Process

Making continuous improvements in the combination products program One question that product sponsors often ask the U.S. Food and Drug Administration (FDA) is whether their medical product will be...

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The Real Reason the EpiPen and Other Off-Patents Are So Expensive

The FDA’s unique position read more

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